HughesMedicine - Pharmacotherapy Pearls from the Internal Medicine Clinical Pharmacist
Wednesday, December 28, 2016
Essentials from the 2016 American Diabetes Association guidelines
Thursday, December 8, 2016
Empagliflozin (Jardiance) new indication - reduces mortality in type 2 diabetes mellitus
A middle-aged patient with diabetes mellitus type 2, CAD, HTN, and obesity is in clinic for a followup appointment 1 year after his diagnosis with diabetes. His medications include lisinopril, atorvastatin, aspirin, and metformin (started 1 year ago and titrated to maximum tolerated dose). Today in clinic, his BP = 148/88 mm Hg, HR = 78 bpm, and HbA1c = 7.6%. In addition to metformin, are there any other antihyperglycemic medications that we can use to reduce his risk of cardiovascular events?
For many years, metformin was the only antihyperglycemic medication proven to reduce mortality in patients with diabetes mellitus type 2 (as per the UKPDS trial). Other classes of medications such as the sulfonylureas, thiazolidinediones, and DPP-4 inhibitors have only been shown to reduce HbA1c and/or microvascular events. This month, the FDA approved
For many years, metformin was the only antihyperglycemic medication proven to reduce mortality in patients with diabetes mellitus type 2 (as per the UKPDS trial). Other classes of medications such as the sulfonylureas, thiazolidinediones, and DPP-4 inhibitors have only been shown to reduce HbA1c and/or microvascular events. This month, the FDA approved
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